Genome-wide methylation analysis in Silver-Russell syndrome, Temple syndrome, and Prader-Willi syndrome.

Kaori Hara-IsonoKeiko MatsubaraTomoko FukeKazuki YamazawaKazuhito SatouNobuyuki MurakamiShinji SaitohKazuhiko NakabayashiKenichiro HataTsutomu OgataMaki FukamiMasayo Kagami

Published in: Clinical epigenetics (2020)

GWMA in three IDs found no methylation signatures shared by SRS, TS14, and PWS groups. Although clustering analysis showed similar mild hypermethylation patterns in TS14 and PWS groups, further study is needed to clarify the effect of methylation patterns on the overlapping phenotypes.

Keyphrases

genome wide
dna methylation
case report
gold nanoparticles
copy number
gene expression
growth hormone