Single cell profiling to determine influence of wheeze and early-life viral infection on developmental programming of airway epithelium.

Sergejs BerdnikovsDawn C NewcombKaitlin E McKernanShelby N KuehnleNana-Fatima HarunaTebeb GebretsadikChristopher McKennanSiyuan MaJacqueline-Yvonne CephusChristian Rosas-SalazarLarry J AndersonJames E Gern Tina V Hartert

Published in: bioRxiv : the preprint server for biology (2024)

Nasal airway epithelial cells from children with wheeze are characterized by altered development and increased susceptibility to RSV infection.

Keyphrases

early life
single cell
rna seq
young adults
high throughput
respiratory syncytial virus
respiratory tract
chronic rhinosinusitis