Mechanisms of Sinoatrial Node Dysfunction in Heart Failure With Preserved Ejection Fraction.
Thássio Ricardo R MesquitaRui ZhangJae Hyung ChoRui ZhangYen-Nien LinLizbeth SanchezJoshua I GoldhaberJoseph K YuJialiu A LiangWeixin LiuNatalia A TrayanovaEugenio CingolaniPublished in: Circulation (2021)
Chronotropic incompetence and SAN dysfunction were seen in both models of HF. We identified that intrinsic abnormalities of SAN structure and function underlie the chronotropic response in HFpEF.
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