Synthesis of novel azasugar-containing 2'β-C-Me 9-deaza nucleosides as potential anti-hepatitis C virus agents.
Pravin L KotianMinwan WuAjit GhoshKevin J PolachYahya El-KattanV Satish KumarTsu-Hsing LinXiaogang ChengShanta BantiaKrishnan RamanPooran ChandYarlagadda S BabuPublished in: Nucleosides, nucleotides & nucleic acids (2022)
As a part of our ongoing discovery efforts exploring azasugar as agents for treating various unmet medical needs, we prepared analogs of azasugar as potential anti-hepatitis C virus (HCV) agents. Herein we describe the synthesis of novel 2'β-C-Me 9-deazanucleoside azasugar analogs.