Surgical Outcomes Following Neoadjuvant Treatment for Locally Advanced and Borderline Resectable Pancreatic Ductal Adenocarcinoma.

Kai Tai Derek YeungSacheen KumarDavid CunninghamLong R JiaoRicky Harminder Bhogal

Published in: Annals of surgery open : perspectives of surgical history, education, and clinical approaches (2024)

Neoadjuvant chemotherapy followed by CRT compared to chemotherapy alone for resected BD and LA PDAC was demonstrated to significantly improve median OS, in particular, in patients with R1 resection margins, ypN1 nodal status, and perivascular invasion.

Keyphrases

locally advanced
neoadjuvant chemotherapy
rectal cancer
lymph node
squamous cell carcinoma
radiation therapy
sentinel lymph node
early stage
heart failure
combination therapy
left ventricular