Insulin protects against type 1 diabetes mellitus-induced aortopathy associated with the inhibition of biomarkers of vascular injury in rats.

Ismaeel Bin-JaliahPeter W HewettFahaid Al-HashemMohamed A HaidaraDina H Abdel KaderM D MorsyBahjat Al-Ani

Published in: Archives of physiology and biochemistry (2019)

We demonstrate effective protection by insulin against T1DM-induced aortopathy in rats, which is associated with the inhibition of vascular injury biomarkers.

Keyphrases

glycemic control
type diabetes
high glucose
aortic valve
diabetic rats
drug induced
endothelial cells
insulin resistance
skeletal muscle