Design, synthesis, antifungal activity and molecular docking of ring-opened pimprinine derivative containing (thio)amide structure.

Lan ChengJing-Rui LiuJia-Mu LiuDale GuoFang DengQiang BianHaifeng ZhangXinya HanAbdallah S AliWei-Hua ZhangMing-Zhi ZhangYu-Cheng Gu

Published in: Pest management science (2023)

The designed and optimized derivative 3o of ring-opening pimprinine base has good antifungal activity and can be used as a new antifungal drug for further research. This article is protected by copyright. All rights reserved.

Keyphrases

molecular docking
molecular dynamics simulations
candida albicans
water soluble
emergency department
adverse drug
drug induced