The ACTN3 R577X polymorphism is associated with metabolic alterations in a sex-dependent manner in subjects from western Mexico.
Elisa Barrón-CabreraNathaly Torres-CastilloKarina González-BecerraEloy A Zepeda-CarrilloRafael Torres-ValadezIván Hernández-CañaveralMartínez-López ErikaPublished in: Journal of human nutrition and dietetics : the official journal of the British Dietetic Association (2021)
The ACTN3 R577X polymorphism was associated with metabolic alterations in women and a tendency was observed in men variant carriers. Thus, this common genetic variant could be implicated in the development of chronic metabolic diseases.