Reassessing the Performance of the "Step-By-Step" Approach to Febrile Infants 90 Days of Age and Younger in the Context of the COVID-19 Pandemic: A Multicentric Retrospective Study.
Alexis RybakCamille AupiaisMarie CotillonRomain BasmaciLoïc de PontualStéphane BonacorsiPatricia MarianiLuce LandraudSégolène BrichlerIsabelle PoilaneNaïm OuldaliLuigi TitomanlioPublished in: The Pediatric infectious disease journal (2022)
The "step-by-step" algorithm remains effective to identify infants with bacterial infection but misclassifies most infants with COVID-19 as at high risk of bacterial infection leading to unnecessary cares. An updated algorithm based adding viral testing may be needed to discriminate fever related to isolated COVID-19 in infants <90 days old.