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Role of interleukin-10 in endochondral bone formation in mice: anabolic effect via the bone morphogenetic protein/Smad pathway.

Youn-Kwan JungGun-Woo KimHye-Ri ParkEun-Ju LeeJe-Yong ChoiFrank BeierSeung-Woo Han
Published in: Arthritis and rheumatism (2014)
These results indicate that IL-10 acts as a stimulator of chondrocyte proliferation and chondrogenic or hypertrophic differentiation via activation of the BMP signaling pathway.
Keyphrases
  • signaling pathway
  • mesenchymal stem cells
  • epithelial mesenchymal transition
  • pi k akt
  • transforming growth factor
  • induced apoptosis
  • high fat diet induced
  • endoplasmic reticulum stress