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The Use of Omic Technologies Applied to Traditional Chinese Medicine Research.

Dalinda-Isabel Sánchez-VidañaRahim RajwaniMan-Sau Wong
Published in: Evidence-based complementary and alternative medicine : eCAM (2017)
Natural products represent one of the most important reservoirs of structural and chemical diversity for the generation of leads in the drug development process. A growing number of researchers have shown interest in the development of drugs based on Chinese herbs. In this review, the use and potential of omic technologies as powerful tools in the modernization of traditional Chinese medicine are discussed. The analytical combination from each omic approach is crucial for understanding the working mechanisms of cells, tissues, organs, and organisms as well as the mechanisms of disease. Gradually, omic approaches have been introduced in every stage of the drug development process to generate high-quality Chinese medicine-based drugs. Finally, the future picture of the use of omic technologies is a promising tool and arena for further improvement in the modernization of traditional Chinese medicine.
Keyphrases
  • induced apoptosis
  • gene expression
  • current status
  • oxidative stress
  • cell death
  • risk assessment
  • endoplasmic reticulum stress
  • climate change