Cumulative effect of metabolic risk factors on left ventricular geometry in those with versus without early-onset type 2 diabetes or prediabetes: The Coronary Artery Risk Development in Young Adults (CARDIA) study.
Yilin YoshidaYuanhao ZuBingbing FanShengxu LiTadashi YoshidaEmily HarvilleTao ZhangSejong BaeJames ShikanyVivian A FonsecaPublished in: Diabetes, obesity & metabolism (2024)
Sustained hyperglycaemia and hyperinsulinaemia are associated with RWT, and those individuals with early T2D/pre-D are potentially at greater risk because of their higher levels of glucose and insulin. Dyslipidaemia was associated with LV structural abnormalities in those individuals with early-onset T2D/pre-D.
Keyphrases
- early onset
- type diabetes
- late onset
- coronary artery
- young adults
- risk factors
- left ventricular
- glycemic control
- heart failure
- pulmonary artery
- acute myocardial infarction
- blood glucose
- mitral valve
- blood pressure
- percutaneous coronary intervention
- pulmonary hypertension
- atrial fibrillation
- weight loss
- ejection fraction