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Genetic analysis of ocular tumour-associated genes using large genomic datasets: insights into selection constraints and variant representation in the population.

Alexander TannerMandeep S SagooOmar A MahrooJose S Pulido
Published in: BMJ open ophthalmology (2024)
Our findings highlight the importance of negative selection in ocular tumour genes, supporting cranial gene conservation. This study provides insights into ocular tumourigenesis and future research avenues.
Keyphrases
  • genome wide
  • genome wide identification
  • copy number
  • optic nerve
  • genome wide analysis
  • dna methylation
  • bioinformatics analysis
  • transcription factor
  • current status
  • rna seq
  • optical coherence tomography
  • single cell