Development and Validation of a Gene Signature Classifier for Consensus Molecular Subtyping of Colorectal Carcinoma in a CLIA-Certified Setting.

Van Karlyle MorrisRajyalakshmi LuthraYusha LiuDzifa Y DuoseWonyul LeeNeelima G ReddyJustin WindhamHuiqin ChenZhimin TongBaili ZhangWei WeiManyam GanirajuBradley M BroomHector A AlvarezAlicia MejiaOmkara VeerankiMark J Routbort Michael James OvermanDavid MenterRiham KatkhudaIgnacio I WistubaJennifer S DavisScott KopetzDipen Maheshbhai Maru

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)

We developed and validated a colorectal cancer CMS assay that is ready for use in clinical trials, to assess prognosis in standard-of-care settings and explore as predictor of therapy response.

Keyphrases

clinical trial
healthcare
palliative care
high throughput
copy number
genome wide
quality improvement
pain management
stem cells
single molecule
mesenchymal stem cells
dna methylation
gene expression
transcription factor
chronic pain
phase iii