Dietary Exposure to the Food Contaminant Deoxynivalenol Triggers Colonic Breakdown by Activating the Mitochondrial and the Death Receptor Pathways.
Delphine PayrosImourana Alassane-KpembiJoelle LaffitteCorine LencinaManon NevesAna Paula BracarensePhilippe PintonSandrine MénardIsabelle P OswaldPublished in: Molecular nutrition & food research (2021)
These results indicate that the dietary exposure to low levels of DON in food targets the colon inducing a health-threatening breakdown of the colonic barrier, highlighting oral exposure to DON as a potential risk factor in triggering IBD.