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Dietary Exposure to the Food Contaminant Deoxynivalenol Triggers Colonic Breakdown by Activating the Mitochondrial and the Death Receptor Pathways.

Delphine PayrosImourana Alassane-KpembiJoelle LaffitteCorine LencinaManon NevesAna Paula BracarensePhilippe PintonSandrine MénardIsabelle P Oswald
Published in: Molecular nutrition & food research (2021)
These results indicate that the dietary exposure to low levels of DON in food targets the colon inducing a health-threatening breakdown of the colonic barrier, highlighting oral exposure to DON as a potential risk factor in triggering IBD.
Keyphrases
  • human health
  • ulcerative colitis
  • risk assessment
  • risk factors
  • healthcare
  • public health
  • oxidative stress
  • signaling pathway
  • mental health
  • climate change
  • health promotion
  • binding protein