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Pityriacitrin marine alkaloids as novel antiviral and anti-phytopathogenic-fungus agents.

Tie-Nan WangShan YangShao-Yang ShiWen-Ying YuanJian-Xin ChenZhong-Yu DuanAi-Dang LuZi-Wen WangQing-Min Wang
Published in: Pest management science (2021)
Pityriacitrin alkaloids and their derivatives were synthesized and evaluated for anti-TMV and fungicidal activities for the first time. Compounds 3a and 5f with excellent activities emerged as new candidates for antiviral research and fungicidal research, respectively. Current work provided a new idea for the molecular design and development of novel plant virus and fungi inhibitors in the future. © 2021 Society of Chemical Industry.
Keyphrases
  • single molecule
  • disease virus
  • structure activity relationship