Target organ damage and incident type 2 diabetes mellitus: the Strong Heart Study.
Giovanni de SimoneWenyu WangLyle G BestFawn YehRaffaele IzzoCostantino MancusiMary J RomanElisa T LeeBarbara V HowardRichard B DevereuxPublished in: Cardiovascular diabetology (2017)
In this population-based study with high prevalence of obesity, TOD precedes clinical appearance of type 2 diabetes and is related to the preceding metabolic status, body composition and inflammatory status. Trial registration Trial registration number: NCT00005134, Name of registry: Strong Heart Study, URL of registry: https://clinicaltrials.gov/ct2/show/NCT00005134, Date of registration: May 25, 2000, Date of enrolment of the first participant to the trial: September 1988.
Keyphrases
- body composition
- phase iii
- study protocol
- clinical trial
- heart failure
- phase ii
- type diabetes
- metabolic syndrome
- oxidative stress
- cardiovascular disease
- computed tomography
- atrial fibrillation
- insulin resistance
- bone mineral density
- health insurance
- open label
- image quality
- contrast enhanced
- skeletal muscle
- glycemic control
- high intensity