Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.

Yunjiao WangGang HeHong TangYouxing ShiXia KangJingtong LyuMin ZhuMei ZhouMingyu YangMiduo MuWan ChenBinghua ZhouJiqiang ZhangKanglai Tang

Published in: Cell proliferation (2019)

Taken together, the findings suggested that aspirin inhibited inflammation and scar formation via regulation of JNK/STAT-3 signalling and decreased rerupture risk of injury tendon. Aspirin could be an ideal therapeutic strategy in tendon injury healing.

Keyphrases

low dose
cardiovascular events
oxidative stress
anterior cruciate ligament reconstruction
antiplatelet therapy
signaling pathway
cell death
rotator cuff
cell proliferation
type diabetes
wound healing
atrial fibrillation