CUB Domain-Containing Protein 1 (CDCP1) Is a Target for Radioligand Therapy in Castration-Resistant Prostate Cancer, including PSMA Null Disease.

Ning ZhaoShalini ChopraKai TrepkaYung-Hua WangSasank SakhamuriNima HooshdaranHyunjung KimJie ZhouShion A LimKevin K LeungEmily A EgusaJun ZhuLi Zhang Adam Foye Renuka Sriram Emily ChanYoungho SeoFelix Y FengEric J SmallJonathan ChouJames A WellsRahul AggarwalKenneth W Bayles

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

The data provide the first evidence supporting CDCP1-directed RLT to treat mCRPC. Expanded studies are warranted to determine whether CDCP1 is a viable drug target for patients with mCPRC.

Keyphrases

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pet imaging
protein protein
stem cells
big data
binding protein
emergency department
computed tomography
machine learning
small molecule
cell therapy