Cognitive decline among older adults: A hidden preexisting condition and its role in 'brain-at-risk' surgical patients.
Connor T A BrennaBeverley A OrserSinziana AvramescuAndrew FleetLilia KaustovStephen ChoiPublished in: Brain and behavior (2021)
Preexisting cognitive impairment is an important, but underrecognized, predictor of postoperative neurocognitive dysfunction, a common and important sequela of surgery. We have applied computerized neuropsychological testing as an efficient and reliable means of detecting preexisting cognitive impairment in two studies of cardiac and noncardiac surgical populations and propose that this tool has great potential in routine clinical diagnosis.
Keyphrases
- cognitive impairment
- cognitive decline
- mild cognitive impairment
- minimally invasive
- coronary artery bypass
- patients undergoing
- oxidative stress
- white matter
- left ventricular
- clinical practice
- resting state
- heart failure
- clinical decision support
- case control
- risk assessment
- percutaneous coronary intervention
- atrial fibrillation
- brain injury