Response Surface Methodology for Spectrophotometric Determination of Two β-Adrenergic Agonists-Terbium Chemosensors in Urine and Pharmaceutical Dosage Forms.

RSM for optimization of spectrophotometric determination of dobutamine and hexoprenaline β-adrenergic agonists-lanthanide chemosensors; PBD was used for screening and CCD for optimization of variables affecting the spectrophotometric method; Determination of dobutamine and hexoprenaline in pure powder, pharmaceutical dosage form, and spiked urine samples was accomplished after method validation.