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C(sp<sup>3</sup>)-H/C(sp<sup>3</sup>)-H Dehydrogenative Radical Coupling of Glycine Derivatives.

Jiayuan WangYouwan YeTongzhi SangChenxing ZhouXiazhen BaoYong YuanCong-De Huo
Published in: Organic letters (2022)
Here we report a general C(sp<sup>3</sup>)-H/C(sp<sup>3</sup>)-H dehydrogenative coupling strategy for the preparation of various natural or unnatural amino acids from readily available glycine derivatives and hydrocarbons through a combination of SET and HAT process.
Keyphrases
  • amino acid
  • room temperature
  • structure activity relationship