The long-term clinical impact of COPD exacerbations: a 3-year observational study (SHERLOCK).
John HaughneyAmanda J LeeMintu NathHana MüllerováUlf HolmgrenEnrico de NigrisBo DingPublished in: Therapeutic advances in respiratory disease (2022)
SHERLOCK highlights that even one moderate exacerbation increases the risk for subsequent exacerbations compared with having no recent prior exacerbations. Reviewing recent exacerbation history to ascertain future exacerbation risk and inform COPD management may reduce hospitalizations and improve patient outcomes.