Impact of Metabolic Syndrome Diagnosis and Its Treatment on Survival of Colorectal Cancer Patients.

Rose N MafianaMaimona S Al-KindiNgozichukwu MafianaAhmed S Al LawatiMansour S Al Moundhri

Published in: Journal of cancer epidemiology (2019)

Our result suggests that, among CRC patients with MetS, taking metformin and statins may improve overall survival, whereas being on insulin may negatively impact CRC prognosis. Further studies are warranted to determine the exact mechanism through which metformin, statins, and insulin exert their effects on CRC survival.

Keyphrases

metabolic syndrome
type diabetes
end stage renal disease
cardiovascular disease
free survival
newly diagnosed
chronic kidney disease
ejection fraction
glycemic control
prognostic factors
peritoneal dialysis
insulin resistance
uric acid
adipose tissue
combination therapy
molecular dynamics