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Effect of post-printing curing time on cytotoxicity of direct printed aligners: A pilot study.

Giorgio IodiceBjorn LudwigElena PolishchukRaffaella PetruzzelliRoberto Di CuntoSoboh HusamMauro Farella
Published in: Orthodontics & craniofacial research (2024)
3D directly printed aligners showed a cytotoxic effect similar to that of thermoformed conventional aligners in terms of fibroblasts growth. A linear trend was found between curing time and cells growth, indicating that directly printed aligners could exhibit higher cytotoxicity if exposed to a longer curing time. This dependence on curing time underscores the importance of following a strict manufacturing process.
Keyphrases
  • low cost
  • induced apoptosis
  • endoplasmic reticulum stress
  • oxidative stress