Adaptive immune changes associate with clinical progression of Alzheimer's disease.
Lynn van OlstAlwin KamermansSem HaltersSusanne M A van der PolErnesto RodriguezInge M W VerberkSanne G S VerberkDanielle W R WesselsCarla Rodriguez-MogedaJan VerhoeffDorine WoutersJan Van den BosscheJuan J Garcia-VallejoAfina W LemstraMaarten E WitteWiesje M van der FlierCharlotte E TeunissenHelga E de VriesPublished in: Molecular neurodegeneration (2024)
Our findings illustrate significant peripheral immune alterations associated with both early and late clinical stages of AD, emphasizing the necessity for further investigation into how these changes influence underlying brain pathology.