Genetic and morphological estimates of androgen exposure predict social deficits in multiple neurodevelopmental disorder cohorts.

Brooke G McKennaYongchao HuangKévin VervierDabney HofammannMary CafferataSeima Al-MomaniFlorencia LowenthalAngela ZhangJin-Young KohSavantha ThenuwaraLeo BrueggemanEthan BahlTanner KoomarNatalie PottschmidtTaylor KalmusLucas CastenTaylor R ThomasJacob J Michaelson

Published in: Molecular autism (2021)

These findings and their replication in the large SPARK cohort lend support to the hypothesis that increasing net androgen exposure diminishes capacity for social functioning in both males and females.

Keyphrases

healthcare
mental health
traumatic brain injury
genome wide
copy number
dna methylation
congenital heart disease