Validity of hospital ICD-10-GM codes to identify acute liver injury in Germany.

Antje Timmer Dominik de SordiSanny KappenKlaus Peter KohseCristina Rebordosa Susanna Perez-GutthannEmmanuelle JacquotNicolas DeltourManel Pladevall

Published in: Pharmacoepidemiology and drug safety (2019)

In safety studies on hepatotoxicity based on routine data using ICD-10-GM discharge codes and when validation of potential cases is not feasible, only the more specific codes should be used to describe ALI, and competing diagnoses for liver injury should be excluded to avoid substantial misclassification.

Keyphrases

drug induced
liver injury
adverse drug
healthcare
electronic health record
clinical practice
emergency department
intensive care unit
machine learning
risk assessment
data analysis