Ion Transport Basis of Diarrhea in a Mouse Model of Adoptive T Cell Transfer Colitis.

Dulari JayawardenaSangeeta TyagiAli NazmiDanyvid Olivares-VillagómezPradeep K Dudeja

Published in: Digestive diseases and sciences (2019)

The studies conducted herein for the first time demonstrate the downregulation of important intestinal ion transporters in proximal and distal colon in T cell transfer colitis mouse model, providing valuable evidence for the ion transporter basis of diarrhea in this chronic model of inflammation.

Keyphrases

mouse model
irritable bowel syndrome
oxidative stress
clostridium difficile
cell proliferation
signaling pathway
minimally invasive
stem cells
bone marrow
electron transfer