Distinct pattern of TP53 mutations in human immunodeficiency virus-related head and neck squamous cell carcinoma.

Frederico O Gleber-NettoMei ZhaoSanchit TrivediJiping WangSamar JasserChristina McDowellHumam KadaraJiexin ZhangJing WangWilliam N WilliamJ Jack LeeMinh Ly NguyenSara I PaiHeather M WallineDong M Shin Matthew J FerrisThomas E CareyJeffrey N MyersCurtis R Pickeringnull null

Published in: Cancer (2017)

HNSCC in HIVIIs presents a distinct pattern of genetic mutations, particularly in the TP53 gene. HIV-related HNSCC may have a distinct biology, and an effect of the HIV virus on the pathogenesis of these tumors should not be ruled out. Cancer 2018;124:84-94. © 2017 American Cancer Society.

Keyphrases

human immunodeficiency virus
antiretroviral therapy
hepatitis c virus
hiv infected
hiv positive
papillary thyroid
hiv aids
squamous cell
hiv testing
copy number
genome wide
lymph node metastasis
south africa
gene expression
drug induced