Systematic analysis of genetic variants in patients with essential tremor.

The discrepancies found in this study indicate the variant rs34090186 in the MC1R gene, some variants of which were reported to be related to increased risk of PD and melanoma, may play a risk role in ET, confirming a potential association between ET and PD. Evidence supporting ET-PD link will continue to accumulate and improve our understanding of any underlying mechanisms for both disorders.