Yunpi Heluo decoction reduces ectopic deposition of lipids by regulating the SIRT1-FoxO1 autophagy pathway in diabetic rats.

Zhu-Jun MaoShiyu LiuTao YuJinglan SuKefu Chai Siying Weng

Published in: Pharmaceutical biology (2022)

YPHL reduced EDL by regulating the SIRT1-FoxO1 autophagy pathway in diabetic rats, which could lead to future perspectives for the treatment of diabetes.

Keyphrases

diabetic rats
oxidative stress
signaling pathway
ischemia reperfusion injury
transcription factor
type diabetes
pi k akt
cell death
endoplasmic reticulum stress
cardiovascular disease
glycemic control
metabolic syndrome
insulin resistance
weight loss