Pattern of Brain Parenchymal Damage Related to Cerebral Small Vessel Disease in Carriers of Rare NOTCH3 Variants.

Zi-Yue LiuFei-Fei ZhaiYi-Jing LiuYi-Jun Zhou Mei-Jun Shu Xiao-Hong HuangFei HanMing-Li LiLi-Xin ZhouJun NiMing Yao Shu-Yang Zhang Li-Ying CuiZheng-Yu JinYi-Cheng Zhu

Published in: Neurology (2023)

variants have a distinct pattern of brain parenchymal damage related to CSVD. Our findings uncover the important genetic predisposition in age-related cerebral small vessel disease in the general population.

Keyphrases

copy number
cerebral ischemia
subarachnoid hemorrhage
white matter
resting state
oxidative stress
cell proliferation
genome wide
brain injury
multiple sclerosis
blood brain barrier