Novel models by machine learning to predict prognosis of breast cancer brain metastases.

Chaofan LiMengjie LiuYinbin ZhangYusheng WangJia LiShiyu SunXuanyu LiuHuizi WuCong FengPeizhuo YaoYiwei JiaYu ZhangXinyu WeiFei WuChong DuXixi ZhaoShuqun ZhangJingkun Qu

Published in: Journal of translational medicine (2023)

We analyzed the clinical features of BCBM patients and constructed 4 machine-learning prognostic models to predict their survival. Our validation results indicate that these models should be highly reproducible in patients with BCBM. We also identified potential prognostic factors for BCBM patients and suggested that primary surgery might improve the survival of BCBM patients with HER2 + and triple-negative subtypes.

Keyphrases

prognostic factors
machine learning
end stage renal disease
chronic kidney disease
brain metastases
ejection fraction
newly diagnosed
peritoneal dialysis
acute coronary syndrome
coronary artery disease
risk assessment