Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination.

Andreas GreinacherThomas ThieleTheodore Earl WarkentinKarin WeisserPaul A KyrleSabine Eichinger

Published in: The New England journal of medicine (2021)

Vaccination with ChAdOx1 nCov-19 can result in the rare development of immune thrombotic thrombocytopenia mediated by platelet-activating antibodies against PF4, which clinically mimics autoimmune heparin-induced thrombocytopenia. (Funded by the German Research Foundation.).

Keyphrases

drug induced
high glucose
multiple sclerosis
venous thromboembolism
diabetic rats
growth factor
oxidative stress