A Low Peripheral Blood CD4/CD8 Ratio Is Associated with Pulmonary Emphysema in HIV.

Matthew TripletteEngi F AttiaKathleen M AkgünGuy W Soo HooMatthew S FreibergAdeel A ButtCherry WongtrakoolMatthew Bidwell GoetzSheldon T BrownChristopher J GraberLaurence HuangKristina Crothers

Published in: PloS one (2017)

A low CD4/CD8 ratio was associated with emphysema and low DLCO in HIV+ subjects, independent of other risk factors and clinical markers of HIV. The CD4/CD8 ratio may be a useful, clinically available, marker for risk of emphysema in HIV+ subjects in the antiretroviral therapy (ART) era.

Keyphrases

antiretroviral therapy
hiv infected
hiv positive
human immunodeficiency virus
hiv aids
hiv infected patients
hiv testing
men who have sex with men
chronic obstructive pulmonary disease
risk factors
peripheral blood
south africa
lung function
idiopathic pulmonary fibrosis
pulmonary hypertension