Cost-effectiveness of CT perfusion for the detection of large vessel occlusion acute ischemic stroke followed by endovascular treatment: a model-based health economic evaluation study.
Henk van VoorstJan W HovingMiou S KoopmanJasper D DaemsDaan PeerlingsErik BuskensHester F LingsmaLudo F M BeenenHugo W A M de JongOlvert A BerkhemerWim H van ZwamYvo B W E M RoosMarianne A A van WalderveenIdo van den WijngaardDiederik W J DippelAlbert J YooBruce C V CampbellWolfgang G KunzBart J EmmerCharles B L M Majoienull nullnull nullnull nullPublished in: European radiology (2023)
• Using CT perfusion to detect an endovascular treatment-eligible occlusions resulted in a health gain and cost savings during 10 years of follow-up. • Depending on the screening costs related to the number of patients needed to image with CT perfusion, cost savings could be considerable (median: € - 3857, IQR: [€ - 5907; € - 1916] per patient). • As the gain in quality adjusted life years was most affected by the sensitivity of CT perfusion-based occlusion detection, additional studies for the diagnostic accuracy of CT perfusion for occlusion detection are required.
Keyphrases
- contrast enhanced
- endovascular treatment
- magnetic resonance imaging
- computed tomography
- dual energy
- image quality
- magnetic resonance
- acute ischemic stroke
- healthcare
- public health
- end stage renal disease
- mental health
- newly diagnosed
- ejection fraction
- health information
- label free
- chronic kidney disease
- climate change
- peritoneal dialysis
- prognostic factors
- machine learning
- risk assessment
- quality improvement