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Characterization of Grades of HPMCAS Spray Dried Dispersions of Itraconazole Based on Supersaturation Kinetics and Molecular Interactions Impacting Formulation Performance.

Asmita AdhikariJames E Polli
Published in: Pharmaceutical research (2020)
In vitro SDD studies and drug-polymer interaction studies provided insight into the performance of HPMCAS grades, as well as the relative contributions of various mechanisms that polymer can promote ITZ absorption from SDD.
Keyphrases
  • case control
  • drug delivery
  • single molecule