How General and Inflammatory Status Impacts on the Prognosis of Patients Affected by Lung Cancer: State of the Art.
Antonio MazzellaRiccardo OrlandiSebastiano MaiorcaClarissa UslenghiMatteo ChiariLorenzo SpaggiariMonica CasiraghiGiorgio Lo IaconoLara GirelliLorenzo SpaggiariPublished in: Biomedicines (2024)
Pulmonary cancer is often associated with systemic inflammation and poor nutritional status and these two aspects are strongly correlated and related to the scarce infiltration of a tumor by immune cells. We reviewed all English literature reviews from 2000 to 2024 from PubMed, Scopus and Google Scholar, including original articles, review articles, and metanalyses. We excluded non-English language articles and case reports/case series. Generally speaking, nutritional and inflammatory status largely affect medium and long-term prognosis in lung cancer patients. A correct stratification of patients could improve their preoperative general functional nutritional and inflammatory status, minimizing, therefore, possible treatment complications and improving long-term prognosis.
Keyphrases
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- ejection fraction
- oxidative stress
- systematic review
- prognostic factors
- peritoneal dialysis
- pulmonary hypertension
- autism spectrum disorder
- papillary thyroid
- patient reported outcomes
- combination therapy
- young adults
- replacement therapy
- drug induced
- lymph node metastasis