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Whole-genome bisulfite sequencing of goat skins identifies signatures associated with hair cycling.

Chao LiYan LiGuangxian ZhouYe GaoSen MaYulin ChenJiuzhou SongXiaolong Wang
Published in: BMC genomics (2018)
Our study provided systematic methylome maps pertaining to the hair cycling stages (anagen vs telogen) at a single-base resolution, and revealed stage-specific methylation loci during cashmere growth or quiescence. Furthermore, we identified epigenetically regulated genes that are potentially involved in HF development and growth in cashmere goats, and likely in other mammal species.
Keyphrases
  • genome wide
  • dna methylation
  • single cell
  • high intensity
  • transcription factor
  • gene expression
  • single molecule
  • heart failure
  • atrial fibrillation
  • genome wide association