The Effects of Single Nucleotide Polymorphisms in Korean Patients with Early-onset Atrial Fibrillation after Catheter Ablation.

Yae Min Park Seung-Young Roh Dae-In Lee Jaemin Shim Jong-Il Choi Sang Weon Park Young Hoon Kim

Published in: Journal of Korean medical science (2020)

Polymorphisms on rs7193343 closest to ZFHX3 (16q22), rs3825214 near to TBX5 (12q24), and rs11047543 near to SOX5 (12p12) modulate the risk for AF recurrence after catheter ablation. The number of risk alleles of these 3 SNPs was an independent predictor of recurrence during long-term follow up in Korean patients with early-onset AF.

Keyphrases

early onset
atrial fibrillation
catheter ablation
left atrial
late onset
left atrial appendage
oral anticoagulants
direct oral anticoagulants
heart failure
percutaneous coronary intervention
stem cells
genome wide
gene expression
dna methylation
left ventricular
breast cancer risk