The strategic biomarker roadmap for the validation of Alzheimer's diagnostic biomarkers: methodological update.
Marina BoccardiAlessandra DodichEmiliano AlbaneseAngèle Gayet-AgeronCristina FestariNicholas J AshtonGérard N BischofKonstantinos ChiotisAntoine LeuzyEmma E WoltersMartin A WalterGil D RabinoviciMaria CarrilloAlexander DrzezgaOskar HanssonAgneta NordbergRik OssenkoppeleVictor L VillemagneBengt WinbladGiovanni B FrisoniValentina GaribottoPublished in: European journal of nuclear medicine and molecular imaging (2021)
This revision allows for more versatile and precise assessment of existing evidence, keeps up with theoretical developments, and helps clinical researchers in producing evidence suitable for evidence-to-decision procedures. Compliance with this methodology is essential to implement AD biomarkers efficiently in clinical research and diagnostics.