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Paraneoplastic Neurologic Symptoms in a Pediatric Patient with Hodgkin Lymphoma.

Claire C BanielSarah S DonaldsonCatherine AftandilianSusan M Hiniker
Published in: Cancer investigation (2021)
Neurological paraneoplastic syndromes are exceedingly rare, and often difficult to recognize clinically. Paraneoplastic achalasia is a condition characterized by new-onset dysphagia that is unrelated to tumor burden, most often due to the development of auto-immune antibodies targeting esophageal tissue. Due to the rarity of this condition, diagnosis is often delayed, leading to increased time to treatment. Here we report a case of a rare paraneoplastic achalasia in a female child with EBV + Hodgkin lymphoma (HL), review literature describing paraneoplastic achalasia, and discuss treatment strategies for improving clinical outcome in these patients.
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