Botanical Drug Puerarin Promotes Neuronal Survival and Neurite Outgrowth against MPTP/MPP+-Induced Toxicity via Progesterone Receptor Signaling.

Yingke ZhaoJia ZhaoXiuying ZhangYuanyuan ChengDan LuoSimon Ming-Yuen LeeLixing LaoJianhui Rong

Published in: Oxidative medicine and cellular longevity (2020)

Puerarin attenuated MPTP- and MPP+-induced toxicity and potentiated neurite outgrowth via PR. These results suggested that puerarin may become an alternative hormone for suppressing MPTP- and MPP+-induced toxicity in neurodegenerative diseases.

Keyphrases

diabetic rats
high glucose
oxidative stress
drug induced
electronic health record