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Vancomycin Pharmacokinetics in Obese Patients with Sepsis or Septic Shock.

Anne M MasichShamir N KalariaJeffrey P GonzalesEmily L HeilAsha L TataKimberly C ClaeysDevang PatelMathangi Gopalakrishnan
Published in: Pharmacotherapy (2020)
To our knowledge, this study provides the first population-based pharmacokinetic model in obese patients with sepsis or septic shock. The nomograms generated from this pharmacokinetic model provide a simplified approach to vancomycin dosing in this patient population.
Keyphrases
  • septic shock
  • obese patients
  • bariatric surgery
  • gastric bypass
  • roux en y gastric bypass
  • methicillin resistant staphylococcus aureus
  • weight loss
  • healthcare
  • case report
  • intensive care unit
  • acute kidney injury