Finding a Needle in the Haystack: Design and Implementation of a Digital Site-less Clinical Study of Serial Rapid Antigen Testing to Identify Asymptomatic SARS-CoV-2 Infection.
Apurv SoniCarly HerbertCaitlin PretzPamela StamegnaAndreas FilippaiosQiming ShiThejas SuvarnaEmma HarmanSummer SchraderChris NowakEric SchrammVik KheterpalStephanie BeharSeanan TarrantJulia FerrantoNathaniel HaferMatthew L RobinsonChad J AchenbachRobert Leo MurphyYukari C ManabeBruce A BartonLaurel O'ConnorNisha FaheyElizabeth OrvekPeter LazarDidem AyturkSteven WongAdrian H ZaiLisa CashmanLokinendi V RaoKatherine L LuzuriagaStephenie C LemonAllison BlodgettWilliam HeetderksJohn BroachDavid D McManusPublished in: medRxiv : the preprint server for health sciences (2022)
The novel, digital site-less approach employed in the 'Test Us At Home' study enabled rapid, efficient, and rigorous evaluation of rapid diagnostics for COVID-19, and can be adapted across research disciplines to optimize study enrollment and accessibility.