Vascular Endothelial Growth Factor A (VEGF-A) and Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2) as Potential Biomarkers for Oral Squamous Cell Carcinoma: A Sri Lankan Study.

Sajith Tilal Edirisinghe Manjula Manoji Weerasekera Dulmini Kavindya De Silva Movini Thisara Devmini Shanaka PathmaperumaGayan Kanchana WijesingheThilini NisansalaAnuradha MaddumageHaizal Mohd Hussaini Alison M Rich Harsha De SilvaMilne TrudyRenuka GoonasingheKanishka De SilvaSurangi Yasawardena

Published in: Asian Pacific journal of cancer prevention : APJCP (2023)

VEGF-A gene expression, serum levels, and tissue VEGFR-2 levels correlated linearly with the stage and grade of the tumor. This study justifies the value of VEGF-A as a potential biomarker in OSCC in early detection of OSCC. More studies are needed to accept the use of VEGF-A.

Keyphrases

vascular endothelial growth factor
endothelial cells
gene expression
dna methylation
binding protein