Incidence of orolingual angioedema after intravenous thrombolysis for stroke.
Bruno CensoriT PartziguianV BonitoM SgarziR RivaD AlimontiE AgazziM VedovelloB FrigeniE VenturelliS La GioiaV BarcellaL DaleffeL LonghiF FerriR CosentiniM R RottoliPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2018)
The incidence of orolingual angioedema was very low in our series. Although OA is usually mild, anaphylactoid reactions may rarely occur, because of the variable degree of activation of the complement system and kinin cascade caused by alteplase. In such instances, admission to neurointensive care may be required. Specific bradykinin antagonists or drugs that target the kallikrein-kinin system are beginning to be used in the more severe cases. Thus, doctors and nurses caring for acute stroke patients need to be able to recognize and treat this complication.
Keyphrases
- healthcare
- risk factors
- acute ischemic stroke
- angiotensin converting enzyme
- drug induced
- liver failure
- emergency department
- pulmonary embolism
- atrial fibrillation
- palliative care
- mental health
- quality improvement
- high dose
- respiratory failure
- knee osteoarthritis
- aortic dissection
- hepatitis b virus
- medical students
- brain injury
- affordable care act
- acute respiratory distress syndrome
- mechanical ventilation