Efficacy and safety of the addition of sitagliptin to treatment of youth with type 2 diabetes and inadequate glycemic control on metformin without or with insulin.
Muhammad Yazid JalaludinAsma DeebPhilip S ZeitlerRaymundo GarciaRon S NewfieldYulia SamoilovaCarmen A RosarioNaim ShehadehChandan K SahaYilong ZhangMartina ZilliLynn W SchererRaymond L H LamGregory T GolmSamuel S EngelKeith D KaufmanR Ravi ShankarPublished in: Pediatric diabetes (2021)
These results do not suggest that addition of sitagliptin to metformin provides durable improvement in glycemic control in youth with T2D. In this study, sitagliptin was generally well tolerated with a safety profile similar to that reported in adults. (ClinicalTrials.gov:NCT01472367,NCT01760447; EudraCT:2011-002529-23/2014-003583-20,2012-004035-23) This article is protected by copyright. All rights reserved.