Next-Generation Sequencing Identifies Pathogenic Variants in HGF, POU3F4, TECTA, and MYO7A in Consanguineous Pakistani Deaf Families.
Xueshuang MeiYaqi ZhouMuhammad AmjadWeiqiang YangRufei ZhuMuhammad AsifHafiz Muhammad Jafar HussainTao YangFurhan IqbalHongyi HuPublished in: Neural plasticity (2021)
Our results showed that the genetic causes of deafness are highly heterogeneous. Even within a single family, the affected members with apparently indistinguishable clinical phenotypes may have different pathogenic variants.